Chinese scientists and their American colleagues have developed two anti-COVID-19 antibody cocktails that could deliver a double whammy against infections caused by a common variant of Omicron.
Scientists at the University of Science and Technology of China, the Chinese Academy of Sciences, and the University of Texas Health Sciences Center at San Antonio have developed divalent nanobodies that can provide broad-spectrum protection against SARS-CoV-2 variants, including Omicron.
Xinhua News Agency reported.
New options covids with adaptive mutations have caused new outbreaks even among vaccinated populations. Therefore, scientists believe that their development will contain the pandemic even when vaccines are no longer so effective.
According to a study published in the journal Cell Research, in two new experimental drugs, researchers combined an antibody called aRBD-2 with two other antibodies aRBD-5 and aRBD-7, respectively. These three nanobodies can neutralize the coronavirus by binding to a highly conserved site in the spike protein of the virus.
Cellular analyzes have shown that the two combined nanobodies, aRBD-2-5 and aRBD-2-7, retain strong neutralizing activity against all major variants tested, including Omicron BA.1, BA.1.1 and BA.2.
Studies have confirmed that the new development effectively “works” to destroy the Omicron BA.1 virus.